ChemOrch
ChemOrch is a framework that synthesizes chemically grounded instruction-response pairs through a two-stage process: task-controlled instruction generation and tool-aware response construction. ChemOrch enables controllable diversity and levels of difficulty for the generated tasks, and ensures response precision through tool planning and distillation, and tool-based self-repair mechanisms.
Publications
Huang, Y.; Jiang, Z.; Luo, X.; Guo, K.; Zhuang, H.; Zhou, Y.; Yuan, Z.; Sun, X.; Schleinitz, J.; Wang, Y.; Zhang, S.; Surve, M.; Chawla, N. V.; Wiest, O.; Zhang, X. ChemOrch: Empowering LLMs with Chemical Intelligence via Groundbreaking Synthetic Instructions NeurIPS 2025, 39, 6578